🧬 PRING Network Explorer

Explore the true PRING PPI graph around a protein, and optionally compare it to a PLM-interact (ESM2-35M) predicted graph.

How to use:

1. Select a species and protein (UniProt ID).
2. Adjust neighborhood hops and max nodes (cap).
3. (Optional) Enable PLM-interact to predict edges and set the probability threshold.
4. Click Visualize graphs to see the true and predicted PPI networks side-by-side, along with a summary of statistics and metrics.
5. Enjoy exploring PPI networks 😎.

Links

• 📦 Dataset: https://huggingface.co/datasets/piaolaidangqu/PRING
• 📄 Paper: https://arxiv.org/abs/2507.05101
• 🤖 PLM-interact model: https://huggingface.co/danliu1226/PLM-interact-35M-humanV11

GPU note (important for embeds):

• This Space uses ZeroGPU. GPU prediction typically requires being signed in on Hugging Face.
• If you’re viewing this embedded, open the Space on Hugging Face and sign in to enable GPU.